刚下了avastin官网的用药指南:* n" @ @* i3 O. l( G7 y2 G
# _4 ]7 Y8 S k. M W2 z) ?% r B
Patients should continue treatment until disease progression or unacceptable toxicity.
6 g: _& g" |0 t: Z! W6 K/ m1 Metastatic Colorectal Cancer (mCRC) ) I# O8 p) c0 X6 W& |* E
The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
! z' t7 B: P0 Q" ]) J. Rintravenous 5-FU-based chemotherapy.
; g2 h9 o T; q; v" J( @, O• Administer 5 mg/kg when used in combination with bolus-IFL.
* r ^% q% s: G• Administer 10 mg/kg when used in combination with FOLFOX4. ) R7 \. w4 Y9 e1 m0 n( R0 y& H% e
2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC) ! p7 N; r h [* k5 h5 K0 x
The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and / t& [: n2 i; m/ S3 m4 l/ O* F
paclitaxel.
. u* v6 a/ r. \3 Metastatic Breast Cancer (MBC)
* {9 f; R. {) {- j+ U The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
: }2 ~9 l6 d Y, `4 Glioblastoma
! x J( I, C Z) c The recommended dose is 10 mg/kg every 2 weeks.
; a7 c# e8 F4 N+ g$ s, T; o5 Metastatic Renal Cell Carcinoma (mRCC)' L9 K) @! r1 ]; c8 q2 r( h- n( k8 M
The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa. - d/ w2 r: A3 \) u; P
" t7 G9 |" S7 L# f. |! W按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。
' L0 U0 H; E. e+ {) C我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |